SLC27A5 Back

solute carrier family 27 (fatty acid transporter), member 5

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NCBI Description of SLC27A5

The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog.

Community Annotation of SLC27A5 Add / Edit SLC27A5: Annotations

No community annotations yet for SLC27A5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC27A5 is highly significantly mutated in
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SLC27A5 is significantly mutated in
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SLC27A5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC27A5