SLC25A6 Back

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6

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NCBI Description of SLC25A6

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.

Community Annotation of SLC25A6 Add / Edit SLC25A6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC25A6 is highly significantly mutated in
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SLC25A6 is significantly mutated in
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SLC25A6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC25A6