SLC25A3 Back

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3

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NCBI Description of SLC25A3

The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated.

Community Annotation of SLC25A3 Add / Edit SLC25A3: Annotations

No community annotations yet for SLC25A3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC25A3 is highly significantly mutated in
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SLC25A3 is significantly mutated in
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SLC25A3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC25A3