SLC25A21 Back

solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SLC25A21
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004].

Community Annotation of SLC25A21 Add / Edit SLC25A21: Annotations

No community annotations yet for SLC25A21.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC25A21 is highly significantly mutated in
(none)
SLC25A21 is significantly mutated in
(none)
SLC25A21 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC25A21