SLC25A12 Back

solute carrier family 25 (mitochondrial carrier, Aralar), member 12

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NCBI Description of SLC25A12
This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene.

Community Annotation of SLC25A12 Add / Edit SLC25A12: Annotations

No community annotations yet for SLC25A12.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC25A12 is highly significantly mutated in
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SLC25A12 is significantly mutated in
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SLC25A12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC25A12