SLC25A10 Back

solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10

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NCBI Description of SLC25A10

This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of SLC25A10 Add / Edit SLC25A10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC25A10 is highly significantly mutated in
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SLC25A10 is significantly mutated in
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SLC25A10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC25A10