SLC24A3 Back

solute carrier family 24 (sodium/potassium/calcium exchanger), member 3

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NCBI Description of SLC24A3
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008].

Community Annotation of SLC24A3 Add / Edit SLC24A3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC24A3 is highly significantly mutated in
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SLC24A3 is significantly mutated in
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SLC24A3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC24A3