SLC24A2 Back

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

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NCBI Description of SLC24A2
This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative splicing results in multiple transcript variants.

Community Annotation of SLC24A2 Add / Edit SLC24A2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC24A2 is highly significantly mutated in
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SLC24A2 is significantly mutated in
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SLC24A2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC24A2