SLC22A8 Back

solute carrier family 22 (organic anion transporter), member 8

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NCBI Description of SLC22A8

This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Community Annotation of SLC22A8 Add / Edit SLC22A8: Annotations

No community annotations yet for SLC22A8.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC22A8 is highly significantly mutated in
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SLC22A8 is significantly mutated in
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SLC22A8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC22A8