SLC16A5 Back

solute carrier family 16, member 5 (monocarboxylic acid transporter 6)

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NCBI Description of SLC16A5
This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants.

Community Annotation of SLC16A5 Add / Edit SLC16A5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC16A5 is highly significantly mutated in
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SLC16A5 is significantly mutated in
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SLC16A5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC16A5