SLC16A1 Back

solute carrier family 16, member 1 (monocarboxylic acid transporter 1)

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NCBI Description of SLC16A1

The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of SLC16A1 Add / Edit SLC16A1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC16A1 is highly significantly mutated in
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SLC16A1 is significantly mutated in
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SLC16A1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC16A1