SLC14A2 Back

solute carrier family 14 (urea transporter), member 2

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NCBI Description of SLC14A2

The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of SLC14A2 Add / Edit SLC14A2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC14A2 is highly significantly mutated in
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SLC14A2 is significantly mutated in
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SLC14A2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC14A2