SLC12A4 Back

solute carrier family 12 (potassium/chloride transporters), member 4

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NCBI Description of SLC12A4

This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of SLC12A4 Add / Edit SLC12A4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC12A4 is highly significantly mutated in
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SLC12A4 is significantly mutated in
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SLC12A4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC12A4