SLC12A2 Back

solute carrier family 12 (sodium/potassium/chloride transporters), member 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SLC12A2
The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of SLC12A2 Add / Edit SLC12A2: Annotations

No community annotations yet for SLC12A2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC12A2 is highly significantly mutated in
(none)
SLC12A2 is significantly mutated in
(none)
SLC12A2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC12A2