SLC12A2 Back

solute carrier family 12 (sodium/potassium/chloride transporters), member 2

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NCBI Description of SLC12A2

The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of SLC12A2 Add / Edit SLC12A2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLC12A2 is highly significantly mutated in
SLC12A2 is significantly mutated in
SLC12A2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLC12A2