SLC11A2 Back

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SLC11A2
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of SLC11A2 Add / Edit SLC11A2: Annotations

No community annotations yet for SLC11A2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC11A2 is highly significantly mutated in
(none)
SLC11A2 is significantly mutated in
(none)
SLC11A2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC11A2