SKAP2 Back

src kinase associated phosphoprotein 2

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NCBI Description of SKAP2

The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.

Community Annotation of SKAP2 Add / Edit SKAP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SKAP2 is highly significantly mutated in
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SKAP2 is significantly mutated in
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SKAP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SKAP2