SKA3 Back

spindle and kinetochore associated complex subunit 3

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NCBI Description of SKA3
This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants.

Community Annotation of SKA3 Add / Edit SKA3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SKA3 is highly significantly mutated in
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SKA3 is significantly mutated in
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SKA3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SKA3