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SIX homeobox 4

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NCBI Description of SIX4
This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of SIX4 Add / Edit SIX4: Annotations

No community annotations yet for SIX4.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SIX4 is highly significantly mutated in
(none)
SIX4 is significantly mutated in
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SIX4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SIX4