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SIX homeobox 3

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NCBI Description of SIX3
This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.

Community Annotation of SIX3 Add / Edit SIX3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SIX3 is highly significantly mutated in
(none)
SIX3 is significantly mutated in
(none)
SIX3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SIX3