SIKE1 Back

suppressor of IKBKE 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SIKE1

SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008].

Community Annotation of SIKE1 Add / Edit SIKE1: Annotations

No community annotations yet for SIKE1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SIKE1 is highly significantly mutated in
(none)
SIKE1 is significantly mutated in
(none)
SIKE1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SIKE1