SIAE Back

sialic acid acetylesterase

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NCBI Description of SIAE
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.

Community Annotation of SIAE Add / Edit SIAE: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SIAE is highly significantly mutated in
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SIAE is significantly mutated in
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SIAE is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SIAE