SHROOM4 Back

shroom family member 4

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NCBI Description of SHROOM4
This gene encodes a member of the APX/Shroom family, which contain an N-terminal PDZ domain and a C-terminal ASD2 motif. The encoded protein may play a role in cytoskeletal architecture. Mutations in this gene have been linked to Stocco dos Santos X-linked mental retardation syndrome. Alternatively spliced transcript variants have been described.

Community Annotation of SHROOM4 Add / Edit SHROOM4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SHROOM4 is highly significantly mutated in
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SHROOM4 is significantly mutated in
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SHROOM4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SHROOM4