SH2D2A Back

SH2 domain protein 2A

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NCBI Description of SH2D2A

This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants.

Community Annotation of SH2D2A Add / Edit SH2D2A: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SH2D2A is highly significantly mutated in
SH2D2A is significantly mutated in
SH2D2A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SH2D2A