SGPP2 Back

sphingosine-1-phosphate phosphotase 2

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NCBI Description of SGPP2

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P (Ogawa et al., 2003 [PubMed 12411432]).[supplied by OMIM, Jun 2009].

Community Annotation of SGPP2 Add / Edit SGPP2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SGPP2 is highly significantly mutated in
SGPP2 is significantly mutated in
SGPP2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SGPP2