SGPP1 Back

sphingosine-1-phosphate phosphatase 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SGPP1
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009].

Community Annotation of SGPP1 Add / Edit SGPP1: Annotations

No community annotations yet for SGPP1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SGPP1 is highly significantly mutated in
(none)
SGPP1 is significantly mutated in
(none)
SGPP1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SGPP1