SGK3 Back

serum/glucocorticoid regulated kinase family, member 3

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NCBI Description of SGK3

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Community Annotation of SGK3 Add / Edit SGK3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SGK3 is highly significantly mutated in
SGK3 is significantly mutated in
SGK3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SGK3