SGIP1 Back

SH3-domain GRB2-like (endophilin) interacting protein 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SGIP1

SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]).[supplied by OMIM, Mar 2008].

Community Annotation of SGIP1 Add / Edit SGIP1: Annotations

No community annotations yet for SGIP1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SGIP1 is highly significantly mutated in
SGIP1 is significantly mutated in
SGIP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SGIP1