SGIP1 Back

SH3-domain GRB2-like (endophilin) interacting protein 1

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NCBI Description of SGIP1
SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]).[supplied by OMIM, Mar 2008].

Community Annotation of SGIP1 Add / Edit SGIP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SGIP1 is highly significantly mutated in
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SGIP1 is significantly mutated in
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SGIP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SGIP1