NCBI Description of SFTPA1
|This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.|
Community Annotation of SFTPA1 Add / Edit SFTPA1: Annotations
No community annotations yet for SFTPA1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.