SFRP4 Back

secreted frizzled-related protein 4

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NCBI Description of SFRP4

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.

Community Annotation of SFRP4 Add / Edit SFRP4: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SFRP4 is highly significantly mutated in
SFRP4 is significantly mutated in
SFRP4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SFRP4