SF1 Back

splicing factor 1

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NCBI Description of SF1

This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants.

Community Annotation of SF1 Add / Edit SF1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SF1 is highly significantly mutated in
(none)
SF1 is significantly mutated in
(none)
SF1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SF1