SEZ6L2 Back

seizure related 6 homolog (mouse)-like 2

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NCBI Description of SEZ6L2
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEZ6L2 is highly significantly mutated in
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SEZ6L2 is significantly mutated in
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SEZ6L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEZ6L2