NCBI Description of SERPING1
|This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.|
Community Annotation of SERPING1 Add / Edit SERPING1: Annotations
No community annotations yet for SERPING1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.