SERPINA5 Back

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

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NCBI Description of SERPINA5
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SERPINA5 is highly significantly mutated in
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SERPINA5 is significantly mutated in
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SERPINA5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SERPINA5