SERPINA10 Back

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10

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NCBI Description of SERPINA10
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of SERPINA10 Add / Edit SERPINA10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SERPINA10 is highly significantly mutated in
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SERPINA10 is significantly mutated in
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SERPINA10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SERPINA10