SEPT8 Back

septin 8

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NCBI Description of SEPT8
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEPT8 is highly significantly mutated in
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SEPT8 is significantly mutated in
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SEPT8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEPT8