SEMG2 Back

semenogelin II

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SEMG2
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20.

Community Annotation of SEMG2 Add / Edit SEMG2: Annotations

No community annotations yet for SEMG2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEMG2 is highly significantly mutated in
(none)
SEMG2 is significantly mutated in
(none)
SEMG2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEMG2