SEMG1 Back

semenogelin I

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NCBI Description of SEMG1

The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.

Community Annotation of SEMG1 Add / Edit SEMG1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEMG1 is highly significantly mutated in
(none)
SEMG1 is significantly mutated in
(none)
SEMG1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SEMG1