SEMA6B Back

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B

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NCBI Description of SEMA6B
This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEMA6B is highly significantly mutated in
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SEMA6B is significantly mutated in
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SEMA6B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEMA6B