SEL1L Back

sel-1 suppressor of lin-12-like (C. elegans)

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NCBI Description of SEL1L
The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of SEL1L Add / Edit SEL1L: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEL1L is highly significantly mutated in
(none)
SEL1L is significantly mutated in
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SEL1L is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEL1L