SEC61A2 Back

Sec61 alpha 2 subunit (S. cerevisiae)

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NCBI Description of SEC61A2

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SEC61A2 is highly significantly mutated in
SEC61A2 is significantly mutated in
SEC61A2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SEC61A2