SEC24A Back

SEC24 related gene family, member A (S. cerevisiae)

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NCBI Description of SEC24A

The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of SEC24A Add / Edit SEC24A: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SEC24A is highly significantly mutated in
SEC24A is significantly mutated in
SEC24A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SEC24A