SEC14L3 Back

SEC14-like 3 (S. cerevisiae)

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NCBI Description of SEC14L3

The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEC14L3 is highly significantly mutated in
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SEC14L3 is significantly mutated in
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SEC14L3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SEC14L3