SEC14L2 Back

SEC14-like 2 (S. cerevisiae)

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NCBI Description of SEC14L2
This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEC14L2 is highly significantly mutated in
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SEC14L2 is significantly mutated in
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SEC14L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEC14L2