SEC13 Back

SEC13 homolog (S. cerevisiae)

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NCBI Description of SEC13

The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.

Community Annotation of SEC13 Add / Edit SEC13: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SEC13 is highly significantly mutated in
SEC13 is significantly mutated in
SEC13 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SEC13