SEC11A Back

SEC11 homolog A (S. cerevisiae)

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NCBI Description of SEC11A
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.

Community Annotation of SEC11A Add / Edit SEC11A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SEC11A is highly significantly mutated in
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SEC11A is significantly mutated in
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SEC11A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SEC11A