SDC4 Back

syndecan 4

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NCBI Description of SDC4

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SDC4 is highly significantly mutated in
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SDC4 is significantly mutated in
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SDC4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SDC4