SDC3 Back

syndecan 3

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NCBI Description of SDC3

The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.

Community Annotation of SDC3 Add / Edit SDC3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SDC3 is highly significantly mutated in
SDC3 is significantly mutated in
SDC3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SDC3