SCNN1G Back

sodium channel, nonvoltage-gated 1, gamma

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NCBI Description of SCNN1G
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SCNN1G is highly significantly mutated in
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SCNN1G is significantly mutated in
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SCNN1G is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SCNN1G