SCN10A Back

sodium channel, voltage-gated, type X, alpha subunit

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NCBI Description of SCN10A

The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SCN10A is highly significantly mutated in
SCN10A is significantly mutated in
SCN10A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SCN10A