SCARF1 Back

scavenger receptor class F, member 1

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NCBI Description of SCARF1

The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants.

Community Annotation of SCARF1 Add / Edit SCARF1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SCARF1 is highly significantly mutated in
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SCARF1 is significantly mutated in
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SCARF1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SCARF1